Protein Science

We offer protein sequencing services - it is the process of determining the amino acid sequence of a protein-based directly on the fragment ions detected in the mass spectrometer. Using special algorithms, our analysis software can interpret and assign the sequences without prior database knowledge from the protein. De novo sequencing is often used for biotherapeutics development, bio-similar antibody characterization, or resolving ambiguity from gene sequencing of the monoclonal antibody.

De novo sequencing is the process of determining the amino acid sequence of a protein-based directly on the fragment ions detected in the mass spectrometer. After sample receipt, the material is purified or concentrated as needed. The protein is then digested using up to selected multi-enzymes to ensure the highest possible sequence coverage. The proteins are then introduced into mass spectrometer after nano-flow liquid chromatography separation. Using special algorithms, our analysis software can interpret and assign the amino acid sequences without any prior knowledge from the protein.

Comprehensive Proteomics Services

Proteomics, as the combination of proteome experimentation and data analysis, analyses protein composition, structure, expression, modification status, and the interactions and connections between proteins at an overall level. Proteomics plays a vital role in biomedical research in the post-genomic era. With the technological revolution and emerging computational and statistical models, proteomic methodology has evolved rapidly in the past decade and shed light on solving complicated biomedical problems.

There is scientific research and clinical practice of existing and emerging high-throughput proteomics approaches, including mass spectrometry, protein pathway array, next-generation tissue microarrays, single-cell proteomics, single-molecule proteomics, Luminex, Simoa and Olink Proteomics.