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Opportunities

Careers at Enzemic

Chemistry

Associate Scientist

    Job Responsibilities:

Under department supervision, plan, setup, monitor and workup chemical reactions and isolate product; optimize reaction conditions for improved yields and outputs; purify compounds by different methods; characterize and identify compounds using MS and NMR; maintain a detailed lab notebook; carry out literature searches and mine information for ongoing work from search engines; maintain equipment, chemical inventory, and provide lab support; run multiple reactions daily and provide data in a detailed report; Plan and execute daily and weekly schedule; perform safe lab practices; comply with Site safety protocols and Site Standard Operating Procedures (SOPs). Perform duties as required

    Skills
    • Ability to work collaboratively as part of a team.
    • Ability to communicate effectively, orally, in writing and to listen actively
    • Ability to apply critical thinking and good problem-solving skills.
    • Demonstrate a willingness to learn.
    • Education and Experience
    • B.S. in Chemistry with 0-5 years’ industry experience.

Bioconjugation

Associate Scientist/Senior Associate Scientist

    Job Responsibilities:

Under department supervision, plan, setup, monitor and purify bioconjugation reaction using aseptic techniques; characterize and identify bioconjugates using LC-MS, HPLC and/or Capillary Electrophoresis; maintain a detailed lab notebook; maintain equipment, and provide lab support; provide data in a detailed report; Plan and execute daily and weekly schedule; perform safe lab practices; comply with Site safety protocols and Site Standard Operating Procedures (SOPs). Perform additional duties as required.

    Skills
    • Ability to work collaboratively as part of a team.
    • Ability to communicate effectively, orally, in writing and to listen actively
    • Ability to apply critical thinking and good problem-solving skills.
    • Demonstrate a willingness to learn.
    • Education and Experience
    • B.S. in Biochemistry, Protein Chemistry, or other related fields with 0-5 years’ industry experience.

Protein Engineering

Scientist

    Job Responsibilities:

Preparation of bioconjugates (e.g., antibody-drug conjugates, protein-drug conjugates, protein-peptide conjugates, peptide-drug conjugates, protein-oligonucleotide conjugates, protein-fluorophore conjugates, protein-chelator conjugates). The Scientist position will work under the tutelage of an experienced Senior Scientist or Principal Scientist of Bioconjugation Chemistry. This role requires excellent communication skills and the ability to work in a dynamic and collaborative environment. This position also offers significant growth opportunities within our growing organization. No previous experience in bioconjugation required.

    Desired Qualifications
    • Degree in Protein Engineering, Cell Biology, Biochemistry, Biology, Molecular Biology, or related discipline, plus 0-1 year of related experience in a pharmaceutical industry setting.
    • Experience with preparation and purification of proteins, antibodies, oligos, and or bioconjugates (< 100 mg) using modern protein purification methodologies such as HPLC, ultrafiltration /diafiltration (UF/DF) and tangential flow filtration (TFF), hydrophobic interaction chromatography (HIC), ion-exchange, affinity chromatography, and/or size-exclusion chromatography (SEC) is required.
    • Strong background in antibody/protein engineering and or molecular biology.
    • Experience in cell-based assays would be an important asset.
    • Experience in monoclonal antibody design & development and biophysical characterization (i.e., FPLC, HPLC, UPLC and mass spectrometry) is needed.
    • Working knowledge in mammalian cell culture including 3D cell culture is needed.
    • Education and Other Skills:

    • BS, MS or PhD in Degree in Protein Engineering, Cell Biology, Biochemistry, Biology, Molecular Biology or related discipline with 0-1 year of pharmaceutical/biotech experience in related field.
    • Needs exposure to the bioanalytical characterization and development of proteins is needed.
    • Possess critical thinking and problem-solving skills.
    • Knowledge or understanding of bioconjugation (mg- to multi-gram preparation) and exposure to the bioanalytical characterization and development of proteins and bioconjugate therapeutics for protein engineering is a plus.